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Epithelial Barrier Protection of Lactoferrin in Inflammatory Bowel Disease The intestinal epithelial barrier integrity is vital to protect the intestinal cells from microbes, and intestinal barrier dysfunction underpins IBD and other diseases (31, 129131)

Regulation of liver inflammatory injury by signal transducer and activator of transcription-6.American Journal of Pathology2000;157 297-302

Parkin GM, Udawela M, Gibbons A, Dean B (2018) Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders

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p16 ink4a is a cyclin-dependent kinase inhibitor that activates retinoblastoma-associated protein and induces cellular senescence [64], while the loss of nuclear HMGB-1 is considered a senescence biomarker [16, 44]

Decreased RBC lifespan : This has been documented in mice (due to splenic macrophage erythrophagocytosis [Libregts et al 2011]) and cats with inflammation, although the mechanism was not elucidated in cats (Weiss and Kriehbiel 1983)